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Granulation

Granulation. A process which causes powdered particles to adhere permanently to each other to form large particles called granules. There are two methods of granulation: wet, and dry. Wet granulation is the method most extensively used in the pharmaceutical industry. In wet granulation, the aggregation of particles is obtained by using a liquid phase where a binder is homogeneously mixed with the powdered product by kneading the mix. The binder is evaporated from the newly formed granules during a drying step.

Things to Consider When Purchasing This Product:

End-point definition, End-point detection method, End-point optimization, End-point reproducibility, End-point scale-up, Power consumption, Specific density, Blade diameter, Blade velocity, Binder amount, Bowl volume, Gravitational constant, Bowl height, Bowl radius, Binder liquid addition rate, Amount of granulating liquid added per unit time, Binder addition time, Particle volume, Wet mass volume, Wet mass, Specific density of particles, Kinematic viscosity, Dynamic viscosity, Torque