Products > Biopharmaceutical Equipment: Manufacturing

Tableting

Biopharmaceutical Tableting. Tableting is the process of forming pharmaceuticals into tablets. The tablet-pressing process requires that all ingredients be dry, powdered, and of uniform grain size. It is critical that the amount of active ingredient is equal in each tablet. Compressed tablets require great pressure to compact the material. If a homogenous mix cannot be obtained with simple mixing, the ingredients must be granulated. Granulation is the process of collecting particles together by creating bonds between them. Two common processes are wet granulation and dry granulation. Wet granulation uses a liquid binder to bond the powder mixture which is subsequently milled to form granules. Dry granulation, which requires a drug with cohesive properties, is conducted on a press, and often requires repeated compaction steps to get the proper result. After granulation the tablets are formed in a tablet press.

Things to Consider When Purchasing This Product:

Tablet dimensions, Tablet shape, Tablet mass, Tablet ingredients, Tablet layers, Tablet impressed letters/numbers, Type of machine, Meets GMP requirements, Windows for observing process, Ease of cleaning and maintenance, Controller, Overload protection unit, Gear drive fully enclosed, Number of die sets, Maximum pressure (kN), Maximum diameter of tablet, Maximum depth of fill, Maximum thickness of tablet, Turret speed, Production capacity, Motor power and electrical requirements, Overall dimensions, Net weight, Certifications, Agency approvals